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Atypical cutaneous findings in a patient with systemic lupus erythematosus

Identifieur interne : 002133 ( Main/Exploration ); précédent : 002132; suivant : 002134

Atypical cutaneous findings in a patient with systemic lupus erythematosus

Auteurs : O. Elkayam [Israël] ; A. Gat [Israël] ; M. Lidgi [Israël] ; R. Segal [Israël] ; M. Yaron [Israël] ; D. Caspi [Israël]

Source :

RBID : ISTEX:6A756A6884703AAB9F20A1B39E16618F89480D62

English descriptors

Abstract

A previouslydiagnosed systemic lupus erythematosuspatient presented with arthralgia, skin rash and muscular weakness. When treated with high-dose corticosteroids and methotrexate she improved, except for a persistent lesion in the hand which evolved into a profound ulcer, along with tender subcutaneous nodules in the calf. A skin biopsy disclosed necrotizing vasculitis with giant cell granuloma revealing acid fast positive bacteria on ziels nilsen staining. A chest X-ray disclosed miliary tuberculosis (TB). The patient was diagnosed as miliary TB with prominent cutaneous involvement and treated with four anti-tuberculous drugs with slow resolution of her systemic, pulmonary and skin signs.

Url:
DOI: 10.1191/0961203303lu376cr


Affiliations:


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Le document en format XML

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<term>Erythema induratum</term>
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<term>Granuloma</term>
<term>Hypersensitivity</term>
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<div type="abstract" xml:lang="en">A previouslydiagnosed systemic lupus erythematosuspatient presented with arthralgia, skin rash and muscular weakness. When treated with high-dose corticosteroids and methotrexate she improved, except for a persistent lesion in the hand which evolved into a profound ulcer, along with tender subcutaneous nodules in the calf. A skin biopsy disclosed necrotizing vasculitis with giant cell granuloma revealing acid fast positive bacteria on ziels nilsen staining. A chest X-ray disclosed miliary tuberculosis (TB). The patient was diagnosed as miliary TB with prominent cutaneous involvement and treated with four anti-tuberculous drugs with slow resolution of her systemic, pulmonary and skin signs.</div>
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